Όλο το DSpace

Πλοήγηση ανά Συγγραφέα "Hatzigeorgiou, A. G."

Αποτελέσματα 1-9 από 9

    • DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways 

      Vlachos, I. S.; Kostoulas, N.; Vergoulis, T.; Georgakilas, G.; Reczko, M.; Maragkakis, M.; Paraskevopoulou, M. D.; Prionidis, K.; Dalamagas, T.; Hatzigeorgiou, A. G. (2012)
      MicroRNAs (miRNAs) are key regulators of diverse biological processes and their functional analysis has been deemed central in many research pipelines. The new version of DIANA-miRPath web server was redesigned from the ...

    • DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs 

      Paraskevopoulou, M. D.; Georgakilas, G.; Kostoulas, N.; Reczko, M.; Maragkakis, M.; Dalamagas, T. M.; Hatzigeorgiou, A. G. (2013)
      Recently, the attention of the research community has been focused on long non-coding RNAs (lncRNAs) and their physiological/pathological implications. As the number of experiments increase in a rapid rate and transcriptional ...

    • DIANA-microT Web server upgrade supports Fly and Worm miRNA target prediction and bibliographic miRNA to disease association 

      Maragkakis, M.; Vergoulis, T.; Alexiou, P.; Reczko, M.; Plomaritou, K.; Gousis, M.; Kourtis, K.; Koziris, N.; Dalamagas, T.; Hatzigeorgiou, A. G. (2011)
      microRNAs (miRNAs) are small endogenous RNA molecules that are implicated in many biological processes through post-transcriptional regulation of gene expression. The DIANA-microT Web server provides a user-friendly interface ...

    • DIANA-microT web server v5.0: service integration into miRNA functional analysis workflows 

      Paraskevopoulou, M. D.; Georgakilas, G.; Kostoulas, N.; Vlachos, I. S.; Vergoulis, T.; Reczko, M.; Filippidis, C.; Dalamagas, T.; Hatzigeorgiou, A. G. (2013)
      MicroRNAs (miRNAs) are small endogenous RNA molecules that regulate gene expression through mRNA degradation and/or translation repression, affecting many biological processes. DIANA-microT web server (http://www.microrn ...

    • DIANA-miRPath v3.0: deciphering microRNA function with experimental support 

      Vlachos, I. S.; Zagganas, K.; Paraskevopoulou, M. D.; Georgakilas, G.; Karagkouni, D.; Vergoulis, T.; Dalamagas, T.; Hatzigeorgiou, A. G. (2015)
      The functional characterization of miRNAs is still an open challenge. Here, we present DIANA-miRPath v3.0 (http://www.microrna.gr/miRPathv3) an online software suite dedicated to the assessment of miRNA regulatory roles ...

    • DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions 

      Vlachos, I. S.; Paraskevopoulou, M. D.; Karagkouni, D.; Georgakilas, G.; Vergoulis, T.; Kanellos, I.; Anastasopoulos, I. L.; Maniou, S.; Karathanou, K.; Kalfakakou, D.; Fevgas, A.; Dalamagas, T.; Hatzigeorgiou, A. G. (2015)
      microRNAs (miRNAs) are short non-coding RNA species, which act as potent gene expression regulators. Accurate identification of miRNA targets is crucial to understanding their function. Currently, hundreds of thousands of ...

    • microTSS: Accurate microRNA transcription start site identification reveals a significant number of divergent pri-miRNAs 

      Georgakilas, G.; Vlachos, I. S.; Paraskevopoulou, M. D.; Yang, P.; Zhang, Y.; Economides, A. N.; Hatzigeorgiou, A. G. (2014)
      A large fraction of microRNAs (miRNAs) are derived from intergenic non-coding loci and the identification of their promoters remains 'elusive'. Here, we present microTSS, a machine-learning algorithm that provides highly ...

    • miRNA Regulons Associated with Synaptic Function 

      Paschou, M.; Paraskevopoulou, M. D.; Vlachos, I. S.; Koukouraki, P.; Hatzigeorgiou, A. G.; Doxakis, E. (2012)
      Differential RNA localization and local protein synthesis regulate synapse function and plasticity in neurons. MicroRNAs are a conserved class of regulatory RNAs that control mRNA stability and translation in tissues. They ...

    • Online resources for miRNA analysis 

      Vlachos, I. S.; Hatzigeorgiou, A. G. (2013)
      Objective: This review aims to provide a brief introduction to each major category of available tools and algorithms for microRNA (miRNA) research, as well as to present some of the most widely used or promising representative ...